{"id":7880,"date":"2026-04-22T07:00:34","date_gmt":"2026-04-21T23:00:34","guid":{"rendered":"https:\/\/rakuten-med.com\/tw\/?post_type=press_releases&#038;p=7880"},"modified":"2026-04-22T06:21:43","modified_gmt":"2026-04-21T22:21:43","slug":"%e6%a8%82%e5%a4%a9%e9%86%ab%e8%97%a5%e6%96%bc-aacr-2026-%e7%99%bc%e8%a1%a8%e8%87%a8%e5%ba%8a%e5%89%8d%e7%a0%94%e7%a9%b6-%e6%8a%91%e5%88%b6cox-2%e5%8f%af%e9%99%8d%e4%bd%8e-pge%e2%82%82-%e4%b8%a6","status":"publish","type":"press_releases","link":"https:\/\/rakuten-med.com\/tw\/news\/press-releases\/2026\/04\/22\/7880\/","title":{"rendered":"\u6a02\u5929\u91ab\u85e5\u65bc AACR 2026 \u767c\u8868\u81e8\u5e8a\u524d\u7814\u7a76 \u6291\u5236COX-2\u53ef\u964d\u4f4e PGE\u2082 \u4e26\u6709\u6548\u6e1b\u5c11\u5149\u514d\u75ab\u6cbb\u7642\u8a98\u767c\u4e4b\u6c34\u816b"},"content":{"rendered":"<div id=\"pl-7880\"  class=\"panel-layout\" ><div id=\"pg-7880-0\"  class=\"panel-grid panel-no-style\" ><div id=\"pgc-7880-0-0\"  class=\"panel-grid-cell\" ><div id=\"panel-7880-0-0-0\" class=\"so-panel widget widget_sow-editor panel-first-child panel-last-child\" data-index=\"0\" ><div\n\t\t\t\n\t\t\tclass=\"so-widget-sow-editor so-widget-sow-editor-base\"\n\t\t\t\n\t\t>\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<ul>\n<li><b><i>\u672c\u7814\u7a76\u9996\u6b21\u767c\u73fe\uff0c\u5149\u514d\u75ab\u6cbb\u7642\u8a98\u767c\u4e4b\u6c34\u816b\u662f\u7531 COX\u20112 \u6d3b\u5316\u6240\u7522\u751f\u7684 PGE<sub>2<\/sub> \u6240\u9020\u6210 \u3002<\/i><\/b><\/li>\n<li><b><i>\u7814\u7a76\u7d50\u679c\u986f\u793a\uff0c\u9810\u9632\u6027\u6291\u5236 COX\u20112 \u80fd\u964d\u4f4e\u6c34\u816b\u53cd\u61c9\u4e26\u63d0\u5347\u5149\u514d\u75ab\u6cbb\u7642\u7684\u5b89\u5168\u6027\u3002<\/i><\/b><\/li>\n<\/ul>\n<p><b>SAN DIEGO \u2014 2026\u5e744\u670821\u65e5 \u2014 <\/b><span style=\"font-weight: 400\">\u5168\u7403\u6027\u751f\u7269\u6280\u8853\u516c\u53f8\u6a02\u5929\u91ab\u85e5\uff08Rakuten Medical, Inc.\uff09\u81f4\u529b\u65bc\u958b\u767c\u53ca\u5546\u696d\u5316\u4ee5 Alluminox\u00ae \u5e73\u53f0\u70ba\u57fa\u790e\u4e4b\u5149\u514d\u75ab\u6cbb\u7642\uff08photoimmunotherapy\uff09\u3002\u672c\u516c\u53f8\u5ba3\u5e03\uff0c\u984c\u70ba\u300c<a href=\"https:\/\/www.abstractsonline.com\/pp8\/#!\/21436\/presentation\/5131\" target=\"_blank\" rel=\"noopener\">COX-2\/PGE2 driven, photoimmunotherapy-induced edema is reduced by prophylactic NSAIDs in mouse tumor models<\/a>\u300d\u4e4b\u6d77\u5831\uff0c\u5df2\u65bc\u4eca\u65e5\u5728\u7f8e\u570b\u52a0\u5dde\u8056\u5730\u7259\u54e5\u8209\u884c\u4e4b\u7f8e\u570b\u764c\u75c7\u7814\u7a76\u5354\u6703\u5e74\u6703\uff08AACR 2026\uff09\u767c\u8868\u3002\u8a72\u6d77\u5831\u63a2\u8a0e\u5149\u514d\u75ab\u6cbb\u7642\u8a98\u767c\u6c34\u816b\u4e4b\u4f5c\u7528\u6a5f\u8f49\uff0c\u4e26\u8a55\u4f30\u900f\u904e\u6291\u5236\u74b0\u6c27\u5316<\/span><span style=\"font-weight: 400\">\u9176<\/span><span style=\"font-weight: 400\">-2\uff08cyclooxygenase<\/span><span style=\"font-weight: 400\">-<\/span><span style=\"font-weight: 400\">2, COX<\/span><span style=\"font-weight: 400\">-<\/span><span style=\"font-weight: 400\">2\uff09\u4ee5\u964d\u4f4e\u6c34\u816b\u4e4b\u6f5b\u529b\u3002<\/span><\/p>\n<p><span style=\"font-weight: 400\">COX-2 \u70ba\u53ef\u8a98\u5c0e\u578b\u9175\u7d20\uff0c\u65bc\u767c\u708e\u72c0\u614b\u4e0b\u8868\u73fe\u91cf\u6703\u4e0a\u5347\u3002\u6a02\u5929\u91ab\u85e5\u81e8\u5e8a\u524d\u7814\u7a76\u986f\u793a\uff0c\u9810\u9632\u6027\u7d66\u4e88\u9078\u64c7\u6027 COX-2 \u6291\u5236\u5291\u53ef\u4f7f\u5149\u514d\u75ab\u6cbb\u7642\u8a98\u767c\u4e4b\u6c34\u816b\u9ad4\u7a4d\u964d\u4f4e\u7d04 30\u201350%\u3002<\/span><\/p>\n<p><span style=\"font-weight: 400\">\u5728\u672c\u6b21AACR \u767c\u8868\u4e2d\u66f4\u9032\u4e00\u6b65\u767c\u73fe\uff0c\u65bc\u5149\u514d\u75ab\u6cbb\u7642\u5f8c\u53ef\u89c0\u5bdf\u5230 COX-2 \u8868\u73fe\u88ab\u8a98\u5c0e\u800c\u4e0a\u5347\uff0c\u4e26\u4f34\u96a8\u524d\u5217\u817a\u7d20 E\u2082\uff08prostaglandin E\u2082, PGE<sub>2<\/sub>\uff09\u4e4b\u5206\u6ccc\u589e\u52a0\u3002\u96d6\u7136\u8207\u9078\u64c7\u6027 COX-2 \u6291\u5236\u5291\u6216\u6cdb COX \u6291\u5236\u5291\u5171\u540c\u57f9\u990a\u4e26\u672a\u6291\u5236 COX-2 \u7684\u8868\u73fe\uff0c\u4f46\u4e0a\u8ff0\u85e5\u7269\u53ef\u6709\u6548\u963b\u65b7 PGE<sub>2<\/sub> \u5206\u6ccc\u3002\u5df2\u77e5\u5728\u767c\u708e\u74b0\u5883\u4e0b\uff0cPGE<sub>2<\/sub> \u4e3b\u8981\u7531 COX-2 \u6d3b\u5316\u6240\u9a45\u52d5\u7522\u751f\uff0c\u4e26\u53ef\u900f\u904e\u63d0\u9ad8\u8840\u7ba1\u901a\u900f\u6027\u800c\u4fc3\u9032\u6c34\u816b\u5f62\u6210\u3002\u91cd\u8981\u7684\u662f\uff0c\u5728\u672c\u7814\u7a76\u6240\u8a55\u4f30\u4e4b\u816b\u7624\u6a21\u578b\u4e2d\uff0cCOX \u6291\u5236\u4e26\u672a\u5f71\u97ff\u5176\u6297\u816b\u7624\u7642\u6548\u3002<\/span><\/p>\n<p><span style=\"font-weight: 400\">\u7d9c\u5408\u800c\u8a00\uff0c\u7814\u7a76\u7d50\u679c\u652f\u6301\uff1a\u5149\u514d\u75ab\u6cbb\u7642\u8a98\u767c\u4e4b\u6c34\u816b\u8207 COX-2 \u88ab\u8a98\u5c0e\u8868\u73fe\u53ca\u4f9d\u8cf4\u5176\u6d3b\u6027\u4e4b PGE<sub>2<\/sub> \u751f\u6210\u76f8\u95dc\uff1b\u800c\u9810\u9632\u6027\u6291\u5236 COX-2 \u53ef\u80fd\u6709\u52a9\u65bc\u7de9\u89e3\u6c34\u816b\u53cd\u61c9\u3002<\/span><\/p>\n<p><span style=\"font-weight: 400\">\u6a02\u5929\u91ab\u85e5\u5c08\u6709 Alluminox\u00ae \u5e73\u53f0\u4e4b\u5149\u514d\u75ab\u6cbb\u7642\uff0c\u4fc2\u5148\u6295\u4e88\u53ef\u9078\u64c7\u6027\u7d50\u5408\u76ee\u6a19\u7d30\u80de\u4e4b\u85e5\u7269\uff0c\u96a8\u5f8c\u4ee5\u96f7\u5c04\u5149\u7167\u5c04\uff1b\u81e8\u5e8a\u524d\u7814\u7a76\u986f\u793a\uff0c\u6b64\u6d41\u7a0b\u53ef\u5feb\u901f\u4e14\u9078\u64c7\u6027\u5730\u7834\u58de\u76ee\u6a19\u7d30\u80de\u4e4b\u7d30\u80de\u819c\u7d50\u69cb\u3002<\/span><\/p>\n<p><span style=\"font-weight: 400\">\u76ee\u524d\uff0c\u65e5\u672c\u6b63\u900f\u904e\u591a\u4e2d\u5fc3\u3001\u7814\u7a76\u8005\u767c\u8d77\u4e4b\u7814\u7a76\uff08investigator-initiated studies\uff09\uff0c\u5728\u771f\u5be6\u4e16\u754c\u60c5\u5883\u4e2d\u8a55\u4f30\u5149\u514d\u75ab\u6cbb\u7642\u8a98\u767c\u6c34\u816b\u4e4b\u8655\u7f6e\u7b56\u7565\u3002\u57fa\u65bc\u672c\u6b21\u81e8\u5e8a\u524d\u7814\u7a76\u767c\u73fe\u8207\u6301\u7e8c\u9032\u884c\u4e4b\u81e8\u5e8a\u7814\u7a76\uff0c\u6a02\u5929\u91ab\u85e5\u5c07\u81f4\u529b\u65bc\u9032\u4e00\u6b65\u63d0\u5347 Alluminox\u00ae\u5e73\u53f0\u4e4b\u5b89\u5168\u6027\u4e26\u964d\u4f4e\u60a3\u8005\u8ca0\u64d4\u3002<\/span><\/p>\n<p><b>AACR 2026 \u767c\u8868\u4e4b\u4e3b\u8981\u7814\u7a76\u7d50\u679c<\/b><\/p>\n<p><b>\u6a19\u984c: COX-2\/PGE2 driven, photoimmunotherapy-induced edema is reduced by prophylactic NSAIDs in mouse tumor models<\/b><\/p>\n<p><b>\u6d77\u5831\u9023\u7d50: <\/b><a href=\"https:\/\/rakuten-med.com\/us\/wp-content\/uploads\/sites\/6\/2026\/04\/Amantea-4297-AACR-2026-poster.pdf\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400\">Download Poster [PDF]<\/span><\/a><\/p>\n<p><b>\u6458\u8981\u865f\u78bc: <\/b><span style=\"font-weight: 400\">4297<\/span><\/p>\n<\/div>\n<\/div><\/div><\/div><\/div><div id=\"pg-7880-1\"  class=\"panel-grid panel-no-style\" ><div id=\"pgc-7880-1-0\"  class=\"panel-grid-cell\" ><div id=\"panel-7880-1-0-0\" class=\"so-panel widget widget_sow-editor panel-first-child panel-last-child\" data-index=\"1\" ><div\n\t\t\t\n\t\t\tclass=\"so-widget-sow-editor so-widget-sow-editor-base\"\n\t\t\t\n\t\t>\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<p><b>\u95dc\u65bc\u6a02\u5929\u91ab\u85e5<br \/>\n<\/b><span style=\"font-weight: 400\">\u6a02\u5929\u91ab\u85e5(Rakuten Medical Inc.)\u662f\u4e00\u5bb6\u5168\u7403\u6027\u751f\u7269\u6280\u8853\u516c\u53f8\uff0c\u81f4\u529b\u65bc\u958b\u767c\u5176\u5c08\u6709 Alluminox<\/span><span style=\"font-weight: 400\">\u00ae<\/span><span style=\"font-weight: 400\"> \u5e73\u53f0\u70ba\u57fa\u790e\u7684\u5149\u514d\u75ab\u7642\u6cd5\u4e26\u5c07\u5176\u5546\u696d\u5316\u3002\u5728\u81e8\u5e8a\u524d\u7814\u7a76\u4e2d\uff0c\u986f\u793a\u9019\u500b\u5e73\u53f0\u80fd\u8a98\u767c\u5feb\u901f\u53ca\u9078\u64c7\u6027\u7684\u627c\u6bba\u7d30\u80de\u8207\u816b\u7624\u58de\u6b7b\u3002\u9664\u65e5\u672c\u5916\uff0c\u6a02\u5929\u91ab\u85e5\u7684\u5149\u514d\u75ab\u7642\u6cd5\u76ee\u524d\u4ecd\u5728\u7814\u767c\u968e\u6bb5\uff0c\u5c1a\u672a\u7372\u5f97\u5176\u4ed6\u570b\u5bb6\u6216\u5730\u5340\u7684\u6b63\u5f0f\u6838\u51c6\u3002\u6a02\u5929\u91ab\u85e5\u79c9\u6301\u300cCONQUER CANCER\uff08\u6230\u52dd\u764c\u75c7\uff09\u300d\u7684\u4f7f\u547d\uff0c\u81f4\u529b\u65bc\u5c07\u5176\u958b\u5275\u6027\u7642\u6cd5\u5118\u901f\u63a8\u5ee3\u81f3\u5168\u7403\u66f4\u591a\u60a3\u8005\u3002\u516c\u53f8\u7e3d\u90e8\u4f4d\u65bc\u7f8e\u570b\uff0c\u4e26\u65bc\u65e5\u672c\u3001\u53f0\u7063\u3001\u745e\u58eb\u53ca\u5370\u5ea6\u8a2d\u6709\u8fa6\u516c\u64da\u9ede\uff0c\u5171\u6a6b\u8de8\u4e94\u500b\u570b\u5bb6\uff0f\u5730\u5340\u3002\u95dc\u65bc\u66f4\u591a\u8cc7\u8a0a\u8acb\u9020\u8a2a\u00a0<\/span><a href=\"https:\/\/rakuten-med.com\/tw\/\"><span style=\"font-weight: 400\">https:\/\/rakuten-med.com\/tw\/<\/span><\/a><span style=\"font-weight: 400\">\u3002<\/span><\/p>\n<p><b>\u95dc\u65bcAlluminox<\/b><span style=\"font-weight: 400\">\u00ae<\/span><b> \u5e73\u53f0<br \/>\n<\/b><span style=\"font-weight: 400\">Alluminox<\/span><span style=\"font-weight: 400\">\u00ae<\/span><span style=\"font-weight: 400\"> \u5e73\u53f0\u662f\u4e00\u500b\u8a66\u9a57\u5e73\u53f0\uff0c\u4ee5\u540d\u70ba\u5149\u514d\u75ab\u7642\u6cd5 (photoimmunotherapy) \u7684\u764c\u75c7\u7642\u6cd5\u4f5c\u70ba\u57fa\u790e;<\/span> <span style=\"font-weight: 400\">\u5149\u514d\u75ab\u7642\u6cd5\u662f\u7531\u7f8e\u570b\u570b\u5bb6\u764c\u75c7\u7814\u7a76\u6240 (National Cancer Institute) \u7684\u5c0f\u6797\u4e45\u9686\u535a\u58eb\u8207\u5718\u968a\u5171\u540c\u958b\u767c\u3002\u6a02\u5929\u91ab\u85e5\u76ee\u524d\u6b63\u5728\u767c\u5c55 Alluminox \u5e73\u53f0\uff0c\u4ee5\u6210\u70ba\u7531\u85e5\u54c1\u3001\u91ab\u7642\u5668\u6750\u548c\u5176\u4ed6\u76f8\u95dc\u7d44\u6210\u90e8\u5206\u6240\u69cb\u6210\u7684\u6280\u8853\u3002\u5e73\u53f0\u7684\u85e5\u54c1\u90e8\u5206\u662f\u7531\u4e00\u500b\u6a19\u9776\u5206\u5b50\u8207\u4e00\u500b\u6216\u591a\u500b\u67d3\u5291\u63a5\u5408\u6240\u69cb\u6210\uff0c\u9032\u800c\u9054\u5230\u9078\u64c7\u6027\u7d30\u80de\u8868\u9762\u53d7\u9ad4\u7d50\u5408\u7684\u7d50\u679c\u3002\u91ab\u7642\u5668\u6750\u90e8\u5206\u662f\u7531\u4e00\u500b\u5149\u6e90\u6240\u69cb\u6210\uff0c\u6703\u767c\u6563\u5149\u7dda\u5c40\u90e8\u7167\u5c04\u76ee\u6a19\u7d30\u80de\uff0c\u4ee5\u77ac\u9593\u6d3b\u5316\u85e5\u7269\u3002 \u6839\u64da\u81e8\u5e8a\u524d\u7684\u8cc7\u6599\uff0c\u986f\u793a\u9019\u500b\u6d3b\u5316\u4f5c\u7528\u80fd\u900f\u904e\u751f\u7269\u7269\u7406\u904e\u7a0b\u7834\u58de\u76ee\u6a19\u7d30\u80de\u7684\u7d30\u80de\u819c\u5b8c\u6574\u6027\uff0c\u9032\u800c\u5f15\u8d77\u76ee\u6a19\u7d30\u80de\u7684\u5feb\u901f\u53ca\u9078\u64c7\u6027\u58de\u6b7b\u3002\u5728 Alluminox \u5e73\u53f0\u4e0a\u958b\u767c\u7684\u7642\u6cd5\u4e5f\u53ef\u80fd\u6703\u56e0\u70ba\u76ee\u6a19\u7d30\u80de\u7684\u514d\u75ab\u539f\u6027\u7d30\u80de\u6b7b\u4ea1\uff0c\u4ee5\u53ca\uff0f\u6216\u6d88\u9664\u5fae\u74b0\u5883\u4e2d\u7684\u514d\u75ab\u6291\u5236\u5143\u7d20\uff0c\u800c\u9020\u6210\u5c40\u90e8\u6027\u53ca\u5168\u8eab\u6027\u7684\u5148\u5929\u8207\u5f8c\u5929\u514d\u75ab\u6d3b\u5316\u4f5c\u7528\u3002Alluminox \u5c1a\u672a\u5728\u65e5\u672c\u4ee5\u5916\u5730\u5340\u7372\u5f97\u4efb\u4f55\u76e3\u7ba1\u6a5f\u69cb\u7684\u5b89\u5168\u6027\u8207\u6709\u6548\u6027\u6838\u51c6\u3002<\/span><\/p>\n<\/div>\n<\/div><\/div><\/div><\/div><div id=\"pg-7880-2\"  class=\"panel-grid panel-no-style\" ><div id=\"pgc-7880-2-0\"  class=\"panel-grid-cell\" ><div id=\"panel-7880-2-0-0\" class=\"so-panel widget widget_sow-button panel-first-child panel-last-child\" data-index=\"2\" ><div class=\"panel-widget-style panel-widget-style-for-7880-2-0-0\" ><div\n\t\t\t\n\t\t\tclass=\"so-widget-sow-button so-widget-sow-button-flat-6fd36f18507f-7880\"\n\t\t\t\n\t\t><div class=\"ow-button-base ow-button-align-center\"\n>\n\t\t\t<a\n\t\t\t\t\thref=\"https:\/\/rakuten-med.com\/us\/contact\/\"\n\t\t\t\t\tclass=\"rakuten-btn sowb-button ow-icon-placement-left ow-button-hover\" \t>\n\t\t<span>\n\t\t\t\n\t\t\t\u806f\u7d61\u6211\u5011\t\t<\/span>\n\t\t\t<\/a>\n\t<\/div>\n<\/div><\/div><\/div><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>\u672c\u7814\u7a76\u9996\u6b21\u767c\u73fe\uff0c\u5149\u514d\u75ab\u6cbb\u7642\u8a98\u767c\u4e4b\u6c34\u816b\u662f\u7531 COX\u20112 \u6d3b\u5316\u6240\u7522\u751f\u7684 PGE2 \u6240\u9020\u6210 \u3002 \u7814\u7a76\u7d50\u679c\u986f\u793a\uff0c\u9810\u9632\u6027\u6291\u5236 COX\u20112 \u80fd\u964d\u4f4e\u6c34\u816b\u53cd\u61c9\u4e26\u63d0\u5347\u5149\u514d\u75ab\u6cbb\u7642\u7684\u5b89\u5168\u6027\u3002 SAN DIEGO \u2014 2026\u5e744\u670821\u65e5 \u2014 \u5168\u7403\u6027\u751f\u7269\u6280\u8853\u516c\u53f8\u6a02\u5929\u91ab\u85e5\uff08Rakuten Medical, Inc.\uff09\u81f4\u529b\u65bc\u958b\u767c\u53ca\u5546\u696d\u5316\u4ee5 Alluminox\u00ae \u5e73\u53f0\u70ba\u57fa\u790e\u4e4b\u5149\u514d\u75ab\u6cbb\u7642\uff08photoimmunotherapy\uff09\u3002\u672c\u516c\u53f8\u5ba3\u5e03\uff0c\u984c\u70ba\u300cCOX-2\/PGE2 driven, 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