{"id":7545,"date":"2021-12-01T02:54:29","date_gmt":"2021-12-01T10:54:29","guid":{"rendered":"https:\/\/rakuten-med.com\/us\/?post_type=stories&p=7545"},"modified":"2022-07-25T22:56:48","modified_gmt":"2022-07-26T05:56:48","slug":"rakuten-medical-participates-in-the-j-p-morgan-global-healthcare-conference-shanghai-forum","status":"publish","type":"stories","link":"https:\/\/rakuten-med.com\/us\/news\/stories\/2021\/12\/01\/7545\/","title":{"rendered":"Rakuten Medical Participates in the J.P. Morgan Global Healthcare Conference, Shanghai Forum"},"content":{"rendered":"
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Takashi <\/span>Toraishi<\/span>\u00a0Discusses Advances, Opportunities for Immune Therapies<\/span><\/span>\u00a0<\/span><\/h3>\n

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\"J.P.<\/p>\n

President Takashi\u00a0Toraishi\u00a0represented\u00a0Rakuten Medical\u00a0at\u00a0the\u00a0<\/span>J.P. Morgan\u00a0Global Healthcare Conference, Shanghai Forum<\/span>\u00a0\u2013\u00a0held on\u00a0October 12-13<\/span>\u00a0<\/span>as part of the Shanghai Government\u2019s International Biopharma Industry Week Shanghai 2021.\u00a0Toraishi\u00a0was a key participant in a themed panel discussion focusing on\u00a0the advancement and future of immune therapies.<\/span>\u00a0<\/span><\/p>\n

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The session\u00a0\u201cThe Expanding Scope of Immune Therapies: Advances and Opportunities\u201d,\u00a0focused on\u00a0the\u00a0growing importance of combination therapies\u00a0\u2013 a trend\u00a0driven by the greater emphasis on commercialization. With scores of biopharma companies now pursuing\u00a0PD-1\u00a0monotherapies in this segment, investors are shifting their attention to innovative companies that are\u00a0considering ways\u00a0of moving\u00a0beyond\u00a0checkpoint inhibitors and other monotherapies\u00a0to pursue\u00a0patient treatments\u00a0that make use of new technologies and platforms.\u00a0<\/span>\u00a0<\/span><\/p>\n

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Against this background, Toraishi explained Rakuten Medical\u2019s Illuminox\u2122<\/span>\u00a0platform for the development of new cancer therapeutics and its unique position in the immune-oncology sector \u2013 the combination of\u00a0a drug and device, wherein the drug is comprised of a tumor-targeted antibody conjugated with a light-activatable dye, which when activated with non-thermal light, \u201chas the potential\u00a0for rapid and selective cell killing with minimal effects on surrounding normal tissue, as well as\u00a0potential for\u00a0local and systemic induction of innate and adaptive immunity\u201d.\u00a0<\/span>\u00a0<\/span><\/p>\n

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Addressing the core issue for this session \u2013 the challenge to develop new therapies based on\u00a0immune therapy\u2013\u00a0Toraishi\u00a0described\u00a0how\u00a0Rakuten Medical\u00a0continues to evaluate opportunities\u00a0to apply its technology and innovation\u00a0to research applications\u00a0in cancer immunity and vaccination.\u00a0<\/span>\u00a0<\/span><\/p>\n

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The\u00a0COVID-19 pandemic has demonstrated that\u00a0when it comes to health issues, the world is borderless. The same is true for innovation. Innovation needs to be capitalized \u2013 and this is a global-scale challenge.\u00a0 Said\u00a0Toraishi: \u201cRakuten Medical has received commercial approval\u00a0in Japan\u00a0for\u00a0unresectable locally advanced or recurrent head and neck cancer\u00a0and now\u00a0looks\u00a0to partnership and expansion into\u00a0China\u00a0and\u00a0other parts of\u00a0Asia. In every case, we are looking for the best combination for patients.\u201d<\/span>\u00a0<\/span><\/p>\n

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Which companies will succeed in making major advances in terms of safety and efficacy remains to be seen, but expectations are that the market leaders will become apparent in the next three to five years.\u00a0<\/span>\u00a0<\/span><\/p>\n

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About Rakuten Medical, Inc.\u00a0<\/span><\/b>\u00a0<\/span><\/p>\n

Rakuten Medical, Inc. is a global clinical stage biotechnology company developing and commercializing precision, cell-targeting investigational therapies on its Illuminox\u2122<\/span> platform, which, in pre-clinical studies have been shown to induce rapid and selective cell killing and tumor necrosis. Outside of Japan, Illuminox\u2122 therapies have not yet been approved as safe or effective by any regulatory authority. The company\u2019s first drug developed on the Illuminox\u2122 platform, ASP-1929, has received approval from the Japanese Ministry of Health, Labour, and Welfare, and is currently the subject of a global phase 3 clinical trial for recurrent head and neck cancer. Rakuten Medical is committed to its mission to conquer cancer and aims to realize a society where cancer patients can lead fulfilling lives. The company has 6 locations in 5 countries, including the United States, where it is headquartered, Japan, the Netherlands, Taiwan, and Switzerland. For more information, visit\u00a0<\/span>www.rakuten-med.com<\/span><\/a>.<\/span>\u00a0<\/span><\/p>\n

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About Illuminox\u2122 platform <\/span><\/b>\u00a0<\/span><\/p>\n

The Illuminox\u2122 platform is an investigational platform based on a cancer therapy called photoimmunotherapy, which was developed by Dr.<\/span>\u202f<\/span>Hisataka\u00a0Kobayashi<\/span>\u202f<\/span>and team from the National Cancer Institute in<\/span>\u202f<\/span>the United States. Rakuten Medical is developing the Illuminox\u2122 platform as a technology consisting of a drug, device, and other related components. The drug component of the platform consists of a targeting moiety conjugated with one or more dyes leading to selective cell surface binding.<\/span>\u202f<\/span>The device component consists of a light source that locally illuminates the targeted cells with non-thermal light to transiently activate the drug.<\/span>\u202f<\/span> Pre-clinical data have shown that this activation elicits rapid and selective necrosis of targeted cells through a biophysical process that compromises the membrane integrity of the targeted cells. Therapies developed on Illuminox\u2122 may also result in local and systemic innate and adaptive immune activation due to immunogenic cell death of the targeted cells and\/or the removal of immunosuppressive elements within the microenvironment. Outside of<\/span>\u202f<\/span>Japan, Illuminox\u2122 therapies have not yet been approved as safe or effective by any regulatory authority.<\/span>\u00a0<\/span><\/p>\n

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Forward Looking Statements\u00a0<\/span><\/b>\u00a0<\/span><\/p>\n

This Rakuten Medical Story contains forward looking statements that correspond to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. These statements include various risks, uncertainties, and assumptions that may cause Rakuten Medical\u2019s business plans and results to differ from the anticipated results and expectations expressed in these statements. These \u201cforward looking statements\u201d contain information about the status and development of Rakuten Medical products, including, the Illuminox\u2122 platform. The approval and commercial success of Rakuten Medical therapies may not be achieved, and the results and effects shown in pre-clinical studies and data may not be replicated in clinical trials. Forward-looking statements are neither historical facts nor assurances of future performance.\u00a0 Such forward-looking statements are based upon Rakuten Medical\u2019s current beliefs, expectations, and assumptions regarding the future of its business, future plans and strategies, projections, anticipated events and trends, the economy and other future conditions. Because forward-looking statements relate to the future, they are subject to inherent uncertainties, risks and changes in circumstances that are difficult to predict and many of which are outside of Rakuten Medical\u2019s control. Rakuten Medical\u2019s actual results and financial condition may differ materially from those indicated in the forward-looking statements. Therefore, you should not rely on any of these forward-looking statements. In addition, this story uses terms such as \u201cinnate,\u201d \u201ccancer immunity,\u201d \u201cvaccine,\u201d \u201cimmune activation,\u201d to express opinions about clinical trial data and current research. Ongoing clinical trial studies and pre-clinical and clinical research include various risks and uncertainties.\u00a0\u00a0For this reason, actual results may differ from published information. Except to the extent required by applicable law, we undertake no obligation to publicly update this or any other forward-looking statement, whether because of new information, future developments or events, changes in assumptions, changes in the factors affecting forward-looking statements. If one or more forward-looking statement(s) is updated, no inference should be drawn that additional updates will be made to those or other forward-looking statements.<\/span>\u00a0<\/span><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

Takashi Toraishi\u00a0Discusses Advances, Opportunities for Immune Therapies\u00a0   President Takashi\u00a0Toraishi\u00a0represented\u00a0Rakuten Medical\u00a0at\u00a0the\u00a0J.P. Morgan\u00a0Global Healthcare Conference, Shanghai Forum\u00a0\u2013\u00a0held on\u00a0October 12-13\u00a0as part of […]<\/p>\n","protected":false},"author":4,"featured_media":7546,"template":"","meta":{"_acf_changed":false,"_genesis_hide_title":false,"_genesis_hide_breadcrumbs":false,"_genesis_hide_singular_image":false,"_genesis_hide_footer_widgets":false,"_genesis_custom_body_class":"","_genesis_custom_post_class":"","_genesis_layout":""},"class_list":{"0":"post-7545","1":"stories","2":"type-stories","3":"status-publish","4":"has-post-thumbnail","6":"entry"},"yoast_head":"\nRakuten Medical Participates in the J.P. 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